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PhysioEx 9 - • Increasing concentration gradient of the...

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PhysioEx 9: Renal System Physiology Increasing afferent arteriole radius increases the glomerular filtration rate Decreasing afferent arteriole radius a lot can make GFR 0 and nothing moves through the nephron Increasing efferent arteriole radius makes GFR and urine volume decrease Decreasing efferent arteriole radius makes GFR and urine volume increase Increasing pressures increases glomerular pressure, GFR and urine volume; decreasing pressure decreases all those variables too When valve closed, no GFR and urine volume – means kidney not functional b/c not removing waste Simulating Urine Formulation
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Unformatted text preview: • Increasing concentration gradient of the interstitial fluid increases solute concentration and decreases urine volume, which means urine concentration increases • As you add glucose carriers, glucose concentration decreases and it becomes 0 at 400 carriers • Adding aldosterone increases K concentration and decreases urine volume • ADH decreases urine volume a lot more than aldosterone and increases K concentration a lot more • With both ADH and aldosterone, compared to ADH alone, urine concentration and urine volume don’t change, but potassium concentration increases even more...
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