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2002 - Physio Term Test 2

2002 - Physio Term Test 2 - Version A Name Student Number...

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Unformatted text preview: Version A Name Student Number Questions needing attention DEPARTMENT OF PHYSIOLOGY UNTVERSTTY OF TORONTO PSL 200v / 201v Tuesday; January 15, 2002, from 17:30 - 18:30 30 Questions ( 8 pages) DO NOT BEGIN WRITING UNTIL INSTRUCTED TODO so 'W 1. Bubble in your family name beginning in column I of the NAME field. 2. Bubble in your student number, beginning in column 1 of the Student Number ‘ field. ' ' There are several versions of this question paper. Each contains the same. _ questions, but their sequence varies. Question 1 identifies the Version that you have been given. THE CODING OF THIS QUESTION ON YOUR . COMPUTER CARD MUST BE DONE CORRECI'LY AND APPEALS THAT A STUDENT MADE AN ERROR WILL NOT BE ACCEPTED. U.) 4. All questions are of equal value. 5. spelling and/or typing errors do not make a statement ineorrect. 6. l’nvigilators are not permitted to interpret questions to individual students. If you . "' think a question is ambiguous, answer as you understand it, then explain your reasoning on your question book, £193 on the Answer Card. You must also record the guestion number on the line, “Questions needing attention” at the top of this 2826. - . 7. Your computer card must be handed in at the end of the examination. ' ' -. Fill in‘A on your answer sheet . Which of the following acid-base disorders, if any, is most likely to be observed in a patient who takes a life-threatening overdose of a potent sedative (e.g.heroin)? ‘ 'W/m defh/Vy ‘fll/Mcfl _ A. Metabolic acidosis B. Metabolic alkalosis C. No acid-base disorder D. Respiratory acidosis E. Respiratory alkalosis A. Bufi'ering of added hydrogen ions on proteins inside cells B. Bufi‘ering of added hydrogen ions with bicarbonate (HC03—) C. Excretion of ammonium (NI-14+) in the urine D. ' Greater rate of production of carbon dioxide. 13. ' Increasmg ventilahonm's (01 . Each of the following increases renal sodium reabsorptionEXCEPT: Activation of the. sympathetic nervous system I A. B. Decrease in cardiac output ,C. High level of aldosterone _ D. High level of angiotensin II . B. High level of atrial natriuretic peptide The renal proximal convoluted tubule carries out each of the following fimctions EXCEPT: A” _./ A. Reabsorption of filtered bicarbonate (HC03-) B. Reabsorption of filtered glucose C. Reabsorption of majority of filtered sodium D. Secretion of potassium ' i ' ' E. Synthesis of ammonia (NH3) i t i 1 a 1 1 .‘Jitb'iafimumr .. : diuretic hormone, each of the following occurs As 'a result of the action of anti EXCEPT: ‘ ' um um . ‘ A Blood pressure falls/ B. Collecting duct epitheli C. Plasma becomes more dilute. / D. Urine becomes more concentrated . E. Urine volume falls um becomes more permeable to water Which of the follovving situations would lead to the highest 0 rate (assuming that the hydrosta ‘ ' ' both zero)? ' ' 45—2 9 : [o the sequence of electrical changes in in ' ' the temporal sequence of mov , _' The P-wave of the electrocardiogram (ECG) occurs about the same time as the opening of the aortic valve; A. B. as the closing of the mitral valve; C. as the contraction of the atria; D. as the contraction of the ventricles; - E. as the ventricles eject blood into the aorta and pulmonary arteries. ~ 1—0. I - In the atria ' A. there are welltdefined conducting fibers to assure rapid and simultaneous depolarization of all atrial myocytes; B. depolarization spreads from to cell, without a defined conducting pathway; C. the myOcytes contract when calcium is pumped out of the cells; D. relaxation always occurs before ventricular contraction; E. depolarization can spread easily to the ventricles through the valves. 11. The second heart sound occurs A. when the aortic and pulr'nonary valves close; B. when the aortic and. pulmonary valves open; C. at the beginning of ventricular ejection; D. when ventricular-filling ends; . E. at the same time as the QRS complex of the ECG. RV," V _ §___. ' . \ 1,12. The cardiac 93139}; is . . 0): SW KL A; the volume ejected by the right "ventricle during a cardiac cycle; - -. “I )3; the amount of blood pumped in one minute by the left ventricle through the pulmonary circulation; ‘ p C. the amount of blood pumped by the heart in one minute; D. one half the volume of blood pumped through the systemic circulation in B. one mmute; » the product of the end-systolic volume and the heart rate. g Law of the ‘\N, , 13.], Which of the following statements describes best the Frank-Starlin ' heart?: - ‘\ A. when more calcium is released inside the cardiac myocyte, the stroke volume ejected is increased; ' _ - ‘ J3. when the sarcomere is shorter, the stroke volume is increased; C. when the end-diastolic volume is increased, the stroke volume ejected is D. E. increased; ; i < , \/ w ’05ng ’ S 14. r Which of the following statements describes most accurately Whatrhappens when an increase in contractility occurs7; _ at a given end-diastolic volume, the stroke volume ejected is increased; at a given end-systolic volume, the stroke volume ejected is increased; ' eases as sarcomere length increases; the strength of contraction mcr _ \AM the strength of contraction increascs as tendldiastolic volume increases; the contraction becomes faster as end-diasto ' meow? 15- new respond to A. changes in barometric pressure; B. colloid osmotic pressure; C. venous pressure; D. atrial pressure; E. stretching of the arterial Wall by the arterial pressure. /16. ’ In a typical systemic capillary,- the point at which filtration is of the capillary’s length; d osmotic pressure will if the permeability of the wall A. B. increases, the colloi increase; C. if protein concentration in ' the permeability of the capillary will increase; D. E. net filtration tends to be slightly less than reabsorption; none of the above is correct. at A. the end-diastolic volume determines myosin filaments in the myocyte; the number of calcium ions bound to myosin heads is the only factor that determines the force of contraction; osin filaments, the force of B C. y at the same degree of overlap of actin and m contraction is dependent on concentration of intracellular calcium; D timulation or digitalis-like drugs increase the amount of sympathetic 5 calcium released into the cytoplasm of the myocytes when they become depolarized; no effect on the ant—sympathetic innervation has \ E. . stimulation of the p the cytoplasm of the ventricul calcium released into become- depolarized. ar myocytes when they 18‘. Which of the following statements is false?: (it the segment with the highest resistance in the systemic circulation is the ’ arterioles; _ B there are no pulsations in the capillaries; _ . . C the peak blood pressure in the left ventricle and in the. aorta and large arteries is essentially the Same; ' ’ - . 7 D. almost all of the pressure generated by the' heart in the left ventricle is lost (“dissipated”) as the blood reaches the right atrium; _ E the diastolic blood pressure measured in arteries (eg. in the brachial artery 'of the arm) is the same as the pressure in the left ventricle during diastole. A. it regulates the arterial blood pressure by adjusting the cardiac output and peripheral resistance; through sympathetic and para-sympathetic. innervation of the heart and systemic arterioles; it regulateslthe arterial blood pressure in the carotid sinus and aortic arch; ' it regulates the arterial blood pressure onlyvin response to changes in B C position due to gravity; . - " t D. .it maintains a fairly constant arterial blood pressure, when atrial stretch B it regulates arterial blood pressure in response. to changes in para sympathetic nerve activity to the heart. ' ' 20.. When the blood pressure is measured as 126/90 mmHg, A. 126 is the “systolic” pressure; B. the “pulse pressure” is 36 mmHg; C. the “mean” arterial-pressure is 102 mmHg; D. the Korotkofi' sound are not heardabove pressure of 130 ‘mmHg in the cuff; ' E. all of the above statements are true. - 21. The first clotting factor'that the intrinsic and extrinsic pathways have in common A Thromboplastin B. Hageman factor C. - Factor X D Prothrombin Activator E Factor-VIII .lax .to “! r"!.15§§..-.‘2§iiw.'..-....___v'_....-.-. .. gagfifirififi‘viwm J , 22. 23.- 24. 25. 26. PLUGS”? meow? Which of the following contributes most to the viscosity of blood? albumin sodium globulins ' erythrocytes ‘ antibodies Serum is blood plasma minus its: A. B. C. D. E. . sodium ions calcium ions clotting proteins platelets albumins Which of the following is not a component of hemostasis? A. B. C. D. E. platelet plug formation agglutination clot retraction a vascular spasm Hageman Factor two! ‘1 . It is impossible for a type 0+ baby to have a type ' mother. A. B. C. D. E. \ ‘\ AB— 0. 0+ A+ B+ The cardinal signs of inflammation include all of the following except: redness headache heat pain swelling - .ZtZ'; . emu... .. . .v 27. A man with a hematocrit of 50% slipped, sustained a bilateral femoral fracture, and lost three units (1500 cc) of blood On admission to the emergency room soon afterwards, his hematocrit probably would be: A. 50% B. 40% C. 35% D.‘ 60% E. 25% 28. Identify the one INCORRECT statement about phagocytosis. Phagocytosis: A. ’ occurs in the blood stream and in the tissue spaces B is a function of cells which are motile as well as those which are non- motile C. is associated with the specific 1mmune defense system D. _ provides a means of getting rid of worn out cells as well as removing invaders ‘ E can occur with an inert material as well as a bacteria 29. Regarding antibodies, identify the one incorrect statement (ONE INCORRECT) A. Antibodies developed against the haptens can react in secondary infection '. _ B During initial contact with microbial antigen, the antibody response is delayed for several days C. Antibodies cannot directly destroy foreign organisms D The first antibodies produced by newly formed B cells are IgM immunoglobulins. E 75% of all circulating antibodies in a normal individual are IgG immunoglobulins 30. The complement: (ONE CORRECT) A. is found on cell surfaces B is the system that kills microorganisms directly on its own and m conjunction with antibodies -‘ - .C. plays a role in destruction of red blood cells D helps eliminate white blood cells from the body E assists in the destruction of viruses ...
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