lecture 1

lecture 1 - What is microbiology? How do you compare...

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What is microbiology? How do you compare different living things? What are the limits on size for cells? How does genome size go along with cell size? Why is s/v so important? What are the penalties of small size? Why are really small cells interesting? The cell membrane What holds the cell membrane together? How does membrane structure relate to function? How and why does membrane structure vary?
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Who are we studying? The traditional “fve kingdoms”
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Similar morphologies may mask divergent ancestries. Motani 2002
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surface area = 4 π r 2 volume = 4/3 π r 3
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Diffusion is also an important limit on size.
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Thiomargarita namibensis is a huge bacterial cell, but is basically a thin shell of cytoplasm around a chamber of nitrate- enriched water
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OSU Laboratory for the Isolation of Novel Species; sphere = 0.5 µ Pelagibacter ubique ; cell volume about 0.03 μ 3
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scale bar = 1μ, so these cells have a volume of about 0.02 μ 3
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“ARMAN” has a volume of <0.006 μ 3 . Is there a minimum size for a cell?
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lecture 1 - What is microbiology? How do you compare...

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