Review Questions BEFORE lecture 12

Review Questions BEFORE lecture 12 - 7. How can a protein...

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Review Questions BEFORE lecture 12. 1. As always, these are things you should know from Bis2A or previous lectures. If you find yourself unable to answer them, you should review. 2. What is the product of translation? What is consumed in translation? What is the substrate of translation? What is the enzyme/machine involved in translation? What is the relationship between the product of translation and the substrate for translation? 3. What happens at a start codon? What happens at a stop codon? 4. By examining a DNA sequence, can you tell if it is likely to be transcribed? By examining a DNA sequence, can you tell if it encodes an mRNA that is likely to be translated? 5. In Bacterial and Eukaryotic cells, is there any physical separation between transcription and translation? 6. What has to happen to a polypeptide before it becomes a functional protein? Is this process exergonic, endergonic, or “it depends”? What is meant by primary, secondary, tertiary, and quaternary structure?
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Unformatted text preview: 7. How can a protein be reversibly modified to change its conformation and/or activity? How does this relate to the DNA binding proteins discussed in lecture 11? What is meant by allosteric inhibition? What is meant by competitive inhibition? 8. What is meant by feedback regulation? How is cruise control in a car an example of feedback regulation? What is a biological example of feedback regulation? 9. Are regulatory proteins encoded by genes? Why would you expect a sensory/regulatory protein to always be present, even if it is at a relatively low level of abundance? 10. Say that the maximum amount of transcription that is possible from a single promoter is 100 transcript initiations per minute. Design a promoter and regulatory region that could vary from 1 to 100 transcripts per minute using just negative regulation. Design a promoter and regulatory region that could vary from 1 to 100 transcripts per minute using just positive regulation....
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This note was uploaded on 04/05/2011 for the course MIC 102 taught by Professor Appleman during the Fall '08 term at UC Davis.

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