BIS104_F10_Lecture6m

BIS104_F10_Lecture6m - *Problem: the glucose flow alone...

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*Problem: the glucose flow alone tends to increase [Na + ] in the intestinal epithelial cells
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iii. Antiport: Na + /K + -ATPase (Na + -K + pump) The pump is essential for maintaining the osmotic pressure in the epithelial cells and other animal cells! But energy consuming: accounts for 30% of ATP consumption.
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* How does the Na + /K + -ATPase work in a transport cycle? Conformational changes!
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3. Ion Channels: ion selective and fluctuate b/w open and closed states Example: K + channel protein
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a. Membrane potential: due to ion gradients across the membrane a small flow of ion large change in the membrane potential ion channels control the membrane potential
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b. Ion channels are gated by three different means
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*Example: gating a bacterial K + channel
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Rapid movement of leaves in Mimosa and Albizia
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Rapid ion fluxes in ventral and dorsal motor cells
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c. Ion channels in nerve cells *A typical vertebrate neuron Signals/feelings are transmitted along the nerve axon as a local changes in the membrane potential: action potential (nerve impulse) @ 10 m/sec Receive Toward target
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i. Membrane depolarization triggers action potential
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propagated along the axon
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BIS104_F10_Lecture6m - *Problem: the glucose flow alone...

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