BIS104_F10_Lecture23m

BIS104_F10_Lecture23m - 10 Collagen...

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Topic X: Cell-Cell Interaction 1. Plant cell wall and animal extracellular matrix 2. Cell-cell junctions 3. Stem cells and cloning BIS104 (1), Fall 2010 1
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Cells interact with each other and with their surrounding environment 2
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1. Plant cell wall and animal extracellular matrix (ECM) i. Plant cell wall 3 Cellulose: the most abundant polymer !
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Cell wall polysaccharides allow plant cells to acquire their distinct morphologies 4 CELL
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Nascent cellulose microfibrils are arranged in parallel to microtubules beneath the plasma membrane 5
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Cellulose synthase (CESA) complexes track along microtubules 6 YFP CESA CFP Tubulin Merged Why do we care about cellulose so much these days?
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ii. Animal connective tissues 7
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Fibroblasts produce the ECM in connective tissues 8
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iii. Collagens: the most abundant ECM protein 9
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From collagen triple helices to collagen fibrils
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