BIS104_F10_Lecture25m

BIS104_F10_Lecture25m - BIS104(1 Fall 2010 Topic X...

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Topic X: Cell-Cell Interaction 1. Plant cell wall and animal extracellular matrix 2. Cell-cell junctions 3. Stem cells and cloning BIS104 (1), Fall 2010 1
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3. Stem cells and cloning 2
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¾ Stem cells in plants: meristematic cells 3
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¾ Hemopoietic stem cells 4
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¾ All cells have an identical set of genes 5
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¾ Animal embryonic stem (ES) cells are pluripotent 6
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¾ Reproductive and therapeutic cloning 8
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¾ Therapeutic cloning 9
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¾ Induced pluripotent stem (iPS) cells 10
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¾ Cancer stem cells 12
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Topic XI: Uncontrolled Cell Proliferation: Cancer 1. Overview 2. Carcinogens 3. Oncogenes and tumor suppressor genes 4. Genetic disorders in cancer BIS104 (1), Fall 2010 13
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1. Overview Repeated rounds of mutations & cell proliferation cancer 15
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¾ Benign vs. malignant tumors 16
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¾ Cancer incidence as a function of age 17
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¾ Comparison of normal and tumor growth 18
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¾ Young and old cells appear differently 19
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¾ Stages of cancer progression 20
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¾ Pap smear test of uterine cervix 21
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¾ Malignant cancer and metastases 22
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¾ Metastasis 23
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