Chem 481 Study Guide I Fall 2010 Dr. Wood Text Sections: 2.2, 2.3, 3.1, 3.2, 3.3, 3.4, and 4.1 Know the structures, three letter as well as the single letter abbreviations for the standard 20 amino acids. Know what is meant by the designation L amino acid and how to draw the absolute configuration of L isomer in a Fischer projection. Know able to classify amino acids according to their R groups and what properties the individual R groups impart by their structure. Be able to use titration curves to predict the pI, pKa's and most prevalent molecular species at given pH. Recognize a non-standard amino acid or a biomolecule derived from an amino acid precursor i.e. histamine from His or serotonin from Trp). Know how the structure of water influences the solubility of ionic, polar and non-polar compounds and inter and intra molecular forces i.e. charge-charge attractions and repulsions, hydrogen bonding, dipole-dipole interactions, London forces (induced dipole interactions). Know the utility of the Henderson-Hasselbalch equation and buffers
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