Unformatted text preview: -non autonomous – transpoase encoded by another element-SINE (no transpoase) – short interspersed neuclear element which requires LINE elements which stands for long-interspersed nuclear elements and they are long because they contain transpoase-SINE sequence found in humans A. Types B. mechanism of “cut and paste” C. Retroviral integration (look at how HIV works)-HIV is a retrovirus. Retroviral-like elements latent virus. -Envelopt+glycoproteins-capsid ssRNA genome+reverse transcriptase-RNA and capsid released. cDNA-RNASE H degrades the strand of an RNA duplex-integrase acts as a transpoase to insert the HIV genome into the chromosome-LTR- long terminal repeats-target site duplication III. Immunoglobulin Gene rearrangement...
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- Winter '09
- DNA, Genomic Instability, chromosome rearrangements I.