Ethyl Alcohol

Ethyl Alcohol - I. Ethyl Alcohol a. Basics i. Second most...

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I. Ethyl Alcohol a. Basics i. Second most widely used psychoactive substance in the world, after caffeine ii. Can be used as both a sedative and an intoxicant b. Pharmacology i. Major route of administration = alcoholic beverages 1. Concentrations: 12-14% in wine, 3.2-5% in beer, 40-50% in hard liquor. 2. “Proof” = twice the percent of concentration (80 proof = 40% ethanol) ii. Both lipid and water soluble quickly absorbed by the upper intestine (30-90 min to reach max blood concentration), nonspecific depression of all neuronal function. Evenly distributed throughout body, including into brain (and fetus) iii. Metabolism: 1. Most people metabolize 7-8g of 100% alcohol/hour ***Why do you get drunker on an empty stomach? Rapid gastric emptying reduces the time that alcohol is susceptible to be metabolized by alcohol dehydrogenase in the stomach. 2. Legal Blood Alcohol Content (BAC) to drive = .08g% c. Effects i. Depression of behavior, cognition, respiration ii. Dilates blood vessels in skin
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This document was uploaded on 04/06/2011.

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Ethyl Alcohol - I. Ethyl Alcohol a. Basics i. Second most...

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