phys renal 1

phys renal 1 - Kidney Function -regulate extracellular...

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Kidney Function -regulate extracellular fluid -concentrate waste products -remove foreign substances (drugs) -monitor & regulate amount of water (plasma osmolarity) -monitors amount of Na- which reflects the volume of blood plasma -regulate acidity in blood (pH) -secretes hormones -erythropoietin : get more RBC -calcitriol : activated vit. D -renin : causes blood pressure to rise -glucose Anatomy -2 kidneys (bean shape) -size of a computer mouse -in retroperitoneal space Urine flow *kidneys make urine kidney(form)->urete(transport)->bladder(store)-> urethra(release) Micturition = to pee bladder distension>stretch receptor activated>stimulation of spinal center>parasym. stimulation> contraction of detrusor muscle> relaxation of internal sphincter> external sphincter (voluntary) *anticholinergics= used to treat overactive bladder Structure nephron : functional unit *many of the gross structures of the kidney are due to the arrangement of nephrons renal cortex : outer layer *where beginning of nephron is found renal medulla : inner part : striated because of many tubles and blood vessels that run parallel from the cortex to the pelvis renal calyx: the nephron empties at the peaks of the pyramids into the calyx renal pelvix: the funnel-shaped cavity that recieves urine from the calyxes ureter: conveyed from the renal pelvis to the bladder through the ureter : the ureter, pelvic, & calyxes undergo peristaltic contractions to move urine towards the baldder
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The nephron is the functional unit of the kidney. There are typically 1,000,000 nephrons in each kidney. The nephron begins at the renal corpuscle. The renal corpuscle has two parts: the glomerulus, which is formed by capillaries, and the Bowman’s capsule, a double- walled epithelial cup that surrounds the glomerulus. Blood enters the capillaries under pressure. Because of this pressure, fluid passes through the capillary walls and through Bowman’s capsule into the capsular space. The fluid that enters Bowman’s capsule is called the glomerular filtrate. The glomerular filtrate then passes down a series of tubes. Proximal tubule: The first tube that the glomerular filtrate passes into is called the proximal tubule. Reabsorption of most of the filtrate occurs here. Loop of Henle: The next section of the nephron is the Loop of Henle. This section contains two major halves, the descending limb and the thin ascending limb. The thick ascending limb returns back to the originating renal corpuscle. The loop of Henle is important in forming large concentrations of sodium in the interstitium surrounding the loop of Henle. The portion of the tubule that is packed next to the renal corpuscle forms a specialized structure called the macula densa. Distal convoluted tubule: The distal convoluted tubule then follows the Loop of
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This note was uploaded on 04/07/2011 for the course PHYS 100 taught by Professor Balassare during the Fall '10 term at Saint Louis.

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phys renal 1 - Kidney Function -regulate extracellular...

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