NOTES-Chapter 15

NOTES-Chapter 15 - Chapter 15 How do Genes work...

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Chapter 15: How do Genes work? DNA-carbohydrates and nucleotides Experimental Evidence: Griffiths (1928) o Put r and s strain of disease into mice. R strain was benign, s strain is virulent and kills mice o R strain-mice lives o S strain-mice dies o Heat killed s strain-mice lives o Heat killed s strain plus r strain- mice dies o Because of transformation Avery, MacLeod, and McCarty Experiment (1940’s) o Remove the lipids and carbohydrates from a solution of heat- killed s cells. Protein, DNA, and RNA remain o Subject solution to treatments of enzymes to either destroy the proteins, RNA or DNA o Add a small portion of each sample to a culture containing r cells. Observe whether transformation has occurred by testing for the presence of virulent s. Discovered that DNA is the transforming factor because in the tube with DNA removed, no virulent s cells were found. What do genes do? o
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NOTES-Chapter 15 - Chapter 15 How do Genes work...

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