Chpt. 11 - membrane structure

Chpt. 11 - membrane structure - Membrane Structure(Ch 11...

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Membrane Structure (Ch. 11) Membrane lipids: structure and function Membrane proteins: structure and function
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Membrane Lipids: Structure and Function Types of membrane lipids Structural properties- amphiphilic (-pathic) Lipid bilayers- permeability Lipid mobility- fluidity Lipid distribution in subcellular membranes
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Major Types of Membrane Lipids 1. Phospholipids 2. Sterols 3. Glycolipids *** Lipid Classes and Molecular Species 11-7
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Phosphatidylcholine; a common phospholipid 11-6
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Amphiphilic Lipids Spontaneously form Stable Bilayers 11-11
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Lipid Bilayers form stable vesicles (synthetic--liposomes) 11-12
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Separation of 2 Aqueous Compartments: Basis for Life 11-13
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11-20 Lipid Bilayers: Permeability
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Lipid mobility: Fluid bilayer 11-15
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Several Factors Affect Fluidity Temperature (Tm) Gel phase vs Liquid Crystalline phase Lipid “Packing” Fatty acid composition (# double bonds) Phospholipid class composition (cones, cylinders, etc cholesterol content
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Bilayer fluidity (Packing)
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Distribution of Lipids in Subcellular Membranes: VARIABLE (FN?) and ASYMMETRIC 11-17
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Chpt. 11 - membrane structure - Membrane Structure(Ch 11...

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