1-lecture1 - BCHM 561 Harry Charbonneau Professor...

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Unformatted text preview: BCHM 561 Harry Charbonneau Professor Department of Biochemistry Office: HANS 439 Email: charb@purdue.edu Phone: 494-4754 Office Hours: Monday, 9:30-11:00 am Monday, August 25, 2008 1 Teaching Assistant Efrain Sanchez Graduate Student Biochemistry Of fice Hours Mon & Wed 10:30 am-12:30 pm HANS 435 Email: sanchee@purdue.edu Phone: 494-6591 Monday, August 25, 2008 2 TEXTBOOK Biochemistry 6e Berg, Tymoczko, Stryer W.H. Freeman and Company 2006 Textbook is Required (old editions may be okay) Monday, August 25, 2008 3 TEXTBOOK II Highly Recommended but not Required Student Companion to Accompany Biochemistry, Sixth Edition by Richard I. Gumpor t, Nancy Counts Gerber, Frank H. Deis, Roger E. Koeppe , Jeremy M. Berg, John L.Tymoczko, Luber t Str yer (Paperback) Monday, August 25, 2008 4 Please Read the Syllabus to Understand Course Policy Monday, August 25, 2008 5 GRADES Four Exams 3 Evening Exams + Final Exam Exam = 200 points One class meeting canceled for each evening exam Monday, August 25, 2008 6 Grade Scale for BCHM 561 Fall 2008 800 Total Points PERCENTAGE GPA GRADE A+ A A– B+ B B– C+ C C– D+ D D– F Value 4.0 4.0 3.7 3.3 3.0 2.7 2.3 2.0 1.7 1.3 1.0 0.7 0.0 OF TOTAL POINTS !97 93.0-96. 9 90.0-92. 9 87.0-89. 9 83.0-86. 9 80.0-82. 9 77.0-79. 9 73.0-76. 9 70.0-72. 9 67.0-69. 9 63.0-66. 9 60.0-62. 9 <60.0 7 Monday, August 25, 2008 Course Policy • Make-Up Exams • Exam Grade Appeals • Class Attendance • Academic Integrity • E mail Monday, August 25, 2008 8 BLACKBOARD VISTA Not operational ✦ ✦ ✦ ✦ Syllabus / Course Description / Course Policy Lecture Schedule Announcements Lecture Notes ✦ Old Exams / Answers to Fall 08 Exams ✦ Optional Review Sessions Schedule Monday, August 25, 2008 9 Lectures Will be Recorded as Podcasts BoilerCast website http://www.itap.purdue.edu/tlt/Boilercast/ Agriculture / Biochemistry Monday, August 25, 2008 10 Read Text Biochemistry 1 2 Take Brief Notes in Class Lecture Notes Jeremy M. Berg John L Tymoczko Lubert Stryer Structure of Tyr 4 3 Personal Notes Write Carboxylase Rx Self Assessment Quizzes: Companion Structures Reactions Schemes Concepts + to Biochemistry Generate Your Own Personal Notes based on Text & Lectures Monday, August 25, 2008 11 Student Companion to Accompany Biochemistry Student Companion to Accompany Biochemistry, Sixth Edition by Richard I. Gumpor t, Nancy Counts Gerber, Frank H. Deis, Roger E. Koeppe , Jeremy M. Berg, John L.Tymoczko, Luber t Str yer (Paperback) Should Help with Self Assessment Monday, August 25, 2008 12 What is Biochemistry ? an endeavor to understand and explain life in molecular terms Monday, August 25, 2008 13 Monday, August 25, 2008 14 Chemistry Genetics Cell Biology Biochemistry Monday, August 25, 2008 15 Do we have to know structures? Monday, August 25, 2008 16 Do we have to know structures? BIOCHEMISTRY Monday, August 25, 2008 16 Monday, August 25, 2008 17 Chemical structures are part of the language of Biochemistry Fundamental Concept in Biochemistry: Structure is correlated with function Goal: To understand Structure-Function Relationships Monday, August 25, 2008 18 Energy Carrier Base Pairing DNA:DNA RNA:RNA DNA:RNA High Energy Phosphoanhydride Bond γ phosphoryl transfer Monomeric Unit of RNA phosphodiester bond formation in nucleic acids Cell regulation: γ phosphate transferred to Ser/Thr/Tyr side chains of proteins to modify their function Monday, August 25, 2008 19 AMP 3´ 2´ monomer of RNA reduction dAMP monomer of DNA Monday, August 25, 2008 20 ATP 3´, 5´ cAMP mediates hormone action Monday, August 25, 2008 21 cGMP mediates cellular response to hormones required for vision elevated by viagra/cialis cAMP mediates cellular response to distinct hormones required for smell not af fected by viagra/cialis Monday, August 25, 2008 22 ...
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This note was uploaded on 04/11/2011 for the course BCHM 561 taught by Professor Mr. during the Spring '10 term at Purdue University-West Lafayette.

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