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Unformatted text preview: Produces 2 new strands that are each hybrids of new and old strands Requirements for replication What do we need to replicate DNA??? 1.Template: DNA to copy 2.Monomers: nucleotides 3.Enzyme: DNA polymerase 4.Open helix: helicase 5.Torsional strain: topoisomerase (gyrase) 6.More as we see how process works DNA polymerase First one found in e. coli: DNA pol1 Single polypeptide chain Main polymerase from higher eukaryotes is more than 10 polypeptides All DNA polymerases: Synthesize DNA only in 5' -> 3' direction (3' elongation) Require primer (for replication, RNA) short sequence H-bonded to template Template/Primer required for synthesis...
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This note was uploaded on 04/11/2011 for the course BIO 111 taught by Professor Dr. bos during the Winter '10 term at Purdue University-West Lafayette.
- Winter '10
- Dr. Bos