Cellular_Respiration - glucose pyruvate Glycolysis...

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glucose pyruvate Glycolysis Cellular respiration Fermentation Cellular Respiration Metabolism Metaboism: the sum of all chemical reactions in an organism Metabolic reactions often occur in steps Metabolic(or biochemical) pathqway Two types of metabolic reactions: Anabolic reactions-build up molecules Consume energy Catabolic reactions-break down molecules Release energy Metabolism: obtaining energy Glycolysis and cellular respiration Simple to describe: the reverse of photosynthesis The biochemical pathway of breaking down simple sugar(glucose) A series of catabolic reactions Overall reaction: C6H12O6+6O2 6CO2+6H2O
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Glucose as fuel Need energy to create order How do we convert food to energy? The oxidation of glucose is exergonic: Delta G=-686 kcal/mol Given this, does glucose blow up in your cabinets or in your digestive  tract? Stages of glucose oxidation Takes place in a complex set of 4 stages 1. Glycolysis-break down sugar molecules 2. Oxidation of pyruvate 3. Krebs Cycle (TCA, Citric Acid Cycle) 4. Chemiosmosis/electron transport chain last three are called cellular respiration Mechanisms of ATP synthesis ATP synthesis is endergonic
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Energy from glucose oxidation used in the synthesis of ATP Mechanisms 1. Substrate level phosphorylation uses organic P 2. Oxidative phsphorylation uses inorganic P Adenosine triphosphate Substrate level phosphorylation Start with an organic molecule that has a phosphate group (PO4) Transfer that phosphate directly to ADP, making ATP
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Occurs during glycolysis and Krebs cycle Oxidative phosphorylation Transfer of a free(inorganic) phosphate Pi to ADP to make ATP Occurs in cellular respiration Requires intact mitochondria Requires electron transport chain Uses O2 as final electron acceptor Ox phos relies on chemiosmosis
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This note was uploaded on 04/11/2011 for the course BIO 111 taught by Professor Dr. bos during the Fall '10 term at Purdue University-West Lafayette.

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Cellular_Respiration - glucose pyruvate Glycolysis...

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