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Unformatted text preview: complexes and how are they similar to fungal FAS? 4) How many times does the ACP domain interact with/bind the Ketosynthase domain in each extension cycle (ie. each time the chain gets extended by 2 carbons)? What is the oxidation state of the carbon to the thioester in each case (ie. methylene, / unsaturated, -hydroxy, -keto, carboxylate, etc.)? 5) There are two steps in the catalytic mechanism of thioesterase domains. What are these two steps? Which one involves association with ACP? Which one is rate-limiting?...
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This note was uploaded on 04/08/2011 for the course CHEM 157 taught by Professor burkart during the Spring '07 term at UCSD.
- Spring '07