DNARNA-Part3 - (SMP-DNA Their formation involves the...

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Intramolecular triple-helices can be formed by disruption of double- helical DNA with polypurine sequences in mirror repeats . (A mirror repeat is a region such as AGGGGA that has the same base sequence when read in either direction from a central point). Refolding generates a triple-stranded region and a single-stranded loop in a structure called H-DNA . It is believed that triple-strand complexes can be formed during transcription
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Guanine nucleotides and highly G-rich polynucleotides form novel tetrameric structures called G-quartets
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DNA regions with direct repeat symmetry can form structure known as slipped, mispaired DNA
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Unformatted text preview: (SMP-DNA). Their formation involves the unwinding of a double helix and realignment and subsequent pairing of complimentary regions SMP-DNA has not yet been identified in vivo Higher Order DNA Structure-Genomic DNA may be linear or circular-Circular DNA results from the formation of phosphodiester bonds between the 3’ and 5’-ends of linear polynucleotides, which is carried out by the enzyme called DNA ligase-Examples of circular DNAs: bacterial, viral genomes, plasmids (small extrachromo-somal DNAs in bacteria) Enzymes called topoisomerases can regulate the formation of subhelices...
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DNARNA-Part3 - (SMP-DNA Their formation involves the...

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