Unformatted text preview: ion). As the base attacks the substrate, the leaving group will also depart from the molecule. Therefore, a good leaving group will also favor an E2 reaction. There is some give and take between the strength of the base and the quality of the leaving group. If we have a very good leaving group, a weaker base can be used. If we have a very strong base, we can have a weaker leaving group. Lastly, we see that elimination reactions result in the formation of a double bond and the departure of the leaving group. In order for the reaction to occur, we will also need the proton to be beta to the leaving group in order for the double bond to properly be formed....
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- Spring '11
- Chemistry, Nucleophilic substitution