Particle agglutination

Particle agglutination - Agglutination Insoluble or...

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Unformatted text preview: Agglutination Insoluble or particulate Ag or Ab Ag must have at least two determinants Ag excess results in postzone reaction Ab excess results in prozone reactions Reaction time: minutes to hours Test results: qualitative or semiquantitative Precipitation Soluble Ag & Ab Ag must have at least two determinants Ag excess results in postzone reaction Ab excess results in prozone reactions Reaction time: hours to days Test results: qualitative, semi quantitative or quantitative Agglutination vs. Precipitation Rheumatoid Factor RF is not an indication of Rheumatoid arthritis (RA). In latex agglutination procedures, an antibody (or antigen) coats the surface of latex particles (sensitized latex). When a sample containing the specific antigen (or antibody) is mixed with the milky-appearing sensitized latex, it causes visible agglutination (Fig. 1). The degree of agglutination plotted as a function of agglutinant concentration follows a bell-shape...
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This note was uploaded on 04/10/2011 for the course BIOL 4202 taught by Professor Staff during the Spring '11 term at North Texas.

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Particle agglutination - Agglutination Insoluble or...

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