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Leukocytes - Red Blood Cells(Erythrocytes Most abundant...

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Red Blood Cells (Erythrocytes) Most abundant blood cells (99.9% of formed elements) In ♂, 1µL of blood contains 4.5-6.3 million RBCs In ♀, 1µL of blood contains 4.2-5.5 million RBCs Contains the red pigment hemoglobin which binds and transports O 2 and CO 2 Each RBC is a biconcave disc Diameter → 8µm Thickness → 2.5µm
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Sickle-cell Anemia A single mutation in the gene for the β chain of the globin molecule results in abnormal hemoglobin (HbS) Due to the structural change, the β chains link together and become stiff rods under low-O 2 conditions. This causes the RBCs to become sickle-shaped and these malformed RBCs can then block and clog small blood vessels.
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Leukocytes
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Granulocytes Agranulocytes
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Help defend the body against invasion by pathogens, and they remove toxins, wastes, and abnormal/damaged cells A typical µL of blood contains 6000-9000 WBCs. Compare that to RBCs Most of the WBCs in the body at a given moment are in the connective tissue proper or in organs of the lymphatic system Circulating WBCs are just a fraction of the total # Leukocytes ( leuko=white, cyte=cell ) All contain nuclei and organelles unlike… White Blood Cells
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