BIO2A03-2011-L31-template

BIO2A03-2011-L31-template - Biology 2A03 - 2011 Lecture 31...

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Click to edit Master subtitle style 4/13/11 Biology 2A03 - 2011 Lecture 31 Muscle II
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4/13/11 Comparison of skeletal, smooth and cardiac muscle
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4/13/11 Structure of a skeletal muscle fiber (cell) Neuromuscular junction mitochondria SS – subsarcolemmal Multinucleated cells Muscles made up of bundles (fascicles) of muscle fibers myofibrils sarcomere Each fiber (cell) controlled by only 1 motor neuron
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4/13/11 The Sarcomere -Sarcomeres are bordered by Z-lines which anchor thin filaments (actin) -Thick filaments are joined at the M-line (myosin) A band. Entire myosin bundle + overlapping regions of actin I band . Regions of actin filaments which do not overlap myosin. Bisected by Z line H zone. Area of sarcomere between opposing ends of actin filaments
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4/13/11 Thick Filament 100’s of myosins per thick filament arrange in a staggered Each myosin is a dimer of 2 intertwined subunits crossbridge Enzyme activity to hydrolyze ATP
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4/13/11 Tropomyosin partly covers the myosin cross-bridge binding site
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BIO2A03-2011-L31-template - Biology 2A03 - 2011 Lecture 31...

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