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Unformatted text preview: replicas to be made Strands separate; new nucleotides added Result: two identical double helices DNA Polymerase Enzyme that replicates DNA Matches complementary nucleotides, connects sugar & phosphate Mistakes in base pairing About 1 in 100,000 DNA polymerase repairs almost all mistakes (proofreading) Remaining mistakes are mutations Mutation = any change in sequence of DNA bases 1/8/11 3 Results of Mutation Usual result: No effect Sometimes: Harmful (defective protein) Rarely: Evolutionary advantage Cancer Mutations accumulate over years of exposure to mutagens (chemicals, radiation, etc.) Finally, one cell multiplies out of control...
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