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molecular_bio_primer

molecular_bio_primer - Molecular Biology Primer Source...

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  Biocomputing       University of North Texas 1 Molecular Biology Primer Source: www.bioalgorithms.info www.dnaftb.org/dnaftb http://www.dnalc.org/ddnalc/resources/animations.html
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  Biocomputing       University of North Texas 215 How Molecular Biology came about? Microscopic biology began in 1665 Robert Hooke (1635-1703) discovered organisms are made up of cells Matthias Schleiden (1804- 1881) and Theodor Schwann (1810-1882) further expanded the study of cells in 1830s Robert Hooke Theodor Schwann Matthias Schleiden
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  Biocomputing       University of North Texas 315 Major events in the history of Molecular  Biology   1800 - 1870 1865 Gregor Mendel discover the basic rules of heredity of garden pea. An individual organism has two alternative heredity units for a given trait ( dominant trait v.s. recessive trait ) 1869 Johann Friedrich Miescher discovered DNA and named it nuclein. Mendel: The Father of Genetics Johann Miescher
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  Biocomputing       University of North Texas 415 Gregor Mendel’s experiments http://www.dnaftb.org/dnaftb/1/concept/ Friedrich Miescher’s experiments http://www.dnaftb.org/dnaftb/15/concept/
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  Biocomputing       University of North Texas 515 Major events in the history of Molecular  Biology 1940 - 1950 1941 – George Beadle and Edward Tatum identify that genes make proteins 1950 – Edwin Chargaff find Cytosine complements Guanine and Adenine complements Thymine George Beadle Edward Tatum Edwin Chargaff
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  Biocomputing       University of North Texas 615 Major events in the history of Molecular  Biology  1952 - 1960 1952-1953 James D. Watson and Francis H. C. Crick deduced the double helical structure of DNA 1956 George Emil Palade showed the site of enzymes manufacturing in the cytoplasm is made on RNA organelles called ribosomes. James Watson and Francis Crick George Emil Palade
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  Biocomputing       University of North Texas 715 Major events in the history of Molecular Biology 2000-2001 2000 Complete sequence of the euchromatic portion of the Drosophila melanogaster genome 2001 International Human Genome Sequencing :first draft of the sequence of the human genome published
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  Biocomputing       University of North Texas 815 What is Life made of?
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  Biocomputing       University of North Texas 915 Life begins with Cell A cell is a smallest structural unit of an organism that is capable of independent functioning All cells have some common features
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  Biocomputing       University of North Texas 1015 2 types of cells: Prokaryotes  v.s.Eukaryotes
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  Biocomputing       University of North Texas 1115 Prokaryotes and Eukaryotes •According to the most recent evidence, there are three main branches to the tree of  life.  •Prokaryotes include Archaea (“ancient ones”) and bacteria.
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