Set-1-MolBio - Molecular Biology Primer Source:...

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1 .PMFDVMBS #JPMPHZ 1SJNFS Source: www.bioalgorithms.info www.dnaftb.org/dnaftb http://www.dnalc.org/ddnalc/resources/animations.html Wednesday, January 26, 2011
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)PX .PMFDVMBS #JPMPHZ DBNF BCPVU Microscopic biology began in 1665 Robert Hooke (1635-1703) discovered organisms are made up of cells Matthias Schleiden (1804-1881) and Theodor Schwann (1810-1882) further expanded the study of cells in 1830s Robert Hooke Theodor Schwann Matthias Schleiden Wednesday, January 26, 2011
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Major events in the history of Molecular Biology 1800 - 1870 1865 Gregor Mendel discover the basic rules of heredity of garden pea. An individual organism has two alternative heredity units for a given trait ( dominant trait v.s. recessive trait ) 1869 Johann Friedrich Miescher discovered DNA and named it nuclein. Mendel: The Father of Genetics Johann Miescher Wednesday, January 26, 2011
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Gregor Mendel’s experiments http://www.dnaftb.org/dnaftb/1/concept/ Friedrich Miescher’s experiments http://www.dnaftb.org/dnaftb/15/concept/ Wednesday, January 26, 2011
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Major events in the history of Molecular Biology 1940 - 1950 1941 – George Beadle and Edward Tatum identify that genes make proteins 1950 – Edwin Chargaff find Cytosine complements Guanine and Adenine complements Thymine George Beadle Edward Tatum Edwin Chargaff Wednesday, January 26, 2011
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Major events in the history of Molecular Biology 1952 - 1960 1952-1953 James D. Watson and Francis H. C. Crick deduced the double helical structure of DNA 1956 George Emil Palade showed the site of enzymes manufacturing in the cytoplasm is made on RNA organelles called ribosomes. James Watson and Francis Crick George Emil Palade Wednesday, January 26, 2011
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.BKPS FWFOUT JO UIF IJTUPSZ PG .PMFDVMBS #JPMPHZ ±²²²³±²²´ 2000 Complete sequence of the euchromatic portion of the Drosophila melanogaster genome 2001 International Human Genome Sequencing :first draft of the sequence of the human genome published Wednesday, January 26, 2011
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What is Life made of? Wednesday, January 26, 2011
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-JGF CFHJOT XJUI $FMM A cell is a smallest structural unit of an organism that is capable of independent functioning All cells have some common features Wednesday, January 26, 2011
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2 types of cells: Prokaryotes v.s.Eukaryotes Wednesday, January 26, 2011
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•According to the most recent evidence, there are three main branches to the tree of life. •Prokaryotes include Archaea (“ancient ones”) and bacteria. •Eukaryotes are kingdom Eukarya and includes plants, animals, fungi and certain algae. Wednesday, January 26, 2011
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4JHOBMJOH 1BUIXBZT± $POUSPM (FOF Instead of having brains, cells make decision through complex networks of chemical reactions, called pathways Synthesize new materials Break other materials down for spare parts Signal to eat or die Wednesday, January 26, 2011
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$FMMT *OGPSNBUJPO BOE .BDIJOFSZ Cells store all information to replicate itself
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This note was uploaded on 04/15/2011 for the course BIOL 4520 taught by Professor Staff during the Spring '10 term at North Texas.

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Set-1-MolBio - Molecular Biology Primer Source:...

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