1110%20Exam%201%20Practice%20Problems%20-%20Fall%202010 -...

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Short Answer (40 points) Please answer questions concisely and write clearly. Robert, a 63 year-old male, lived alone and worked as a radio journalist and university professor. He was diagnosed with the human immunodeficiency virus (HIV) in 1996. Four years later, Robert was admitted to the hospital with a serious case of pneumonia, and he received highly active antiretroviral therapy (HAART) shortly thereafter. This treatment kept Robert’s HIV symptoms to a minimum, yet he still remained in an extremely immune compromised state. In 2007, Robert noticed a small, painless nodule on the superior, right-central aspect of his forehead. Within three weeks, the nodule grew, and a second, pea-size painless nodule developed in front of his right ear (i.e. preauricular). Concerned by the nodules, Robert visited his dermatologist, Dr. Robbins, to investigate the etiology of the lesions. A punch-biopsy specimen of the lesion was indicative of a small-cell carcinoma. A fine-needle aspiration biopsy of the preauricular mass revealed malignant cells that were consistent with Merkel cell carcinoma. This type of cancer is a rare and deadly form of the disease that easily metastasizes. Merkel cell carcinoma often invades deep in the dermis and is derived from Merkel cells. Risk factors for the disease, as with most skin cancers, involve exposure to
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This note was uploaded on 04/15/2011 for the course BIOL 1110K taught by Professor Kylaross during the Fall '10 term at Georgia State University, Atlanta.

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1110%20Exam%201%20Practice%20Problems%20-%20Fall%202010 -...

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