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Unformatted text preview: one kind of antibody i. All antibodies from 1 B cell have the same specificity ii. Many antibodies = many different B cells IV. Humoral Immune Response Foreign component(virus) appears in body inducing proliferation of pre-existing B cells already committed to making antibodies that recognize antigens (figure 43-15) Figure 43-16 C. Construction of Antibodies a. # of antigens recognized >> # genes devoted to making antibodies Gene rearrangement b. A few DNA sequences encode constant region of Antibodies and many DNA sequences encode variable region of antibodies c. Early B cell maturation: gene rearrangement constant and variable = antibody d. Heavy Chains: 144,000/class (5classes of antibodies) e. Light Chains: 40,000/class f. possible combinations = ~ 10billion actual humans have ~ 2 million g. Figure 43-13 (gene rearrangement)...
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