Chapter13 - 10/26/09 Virus Size Chapter 13 Most are very...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
10/26/09 1 Chapter 13 Viruses Virus Size Most are very small Measured in nm (10 -9 m) Not seen until electron microscope invented Fig. 13.1 All viruses have. .. Genetic material DNA or RNA ds or ss Capsid (protein coat) Many identical proteins that self-assemble into a geometric form Some viruses have… An envelope Derived from host cell upon exit May include viral-specific proteins Spikes Projecting carbohydrate/protein structures Can be means of attachment Important immunologically What’s missing? Enzymes, ribosomes, ATP, amino acids, etc. Viruses are obligatory intracellular parasites They multiply inside a living cell (antiviral drugs therefore a challenge)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10/26/09 2 Vocabulary Virion Infectious particle outside cell Virus General term for all stages Viral Morphology Helical Polyhedral Enveloped Complex Helical Virus (13.4) Polyhedral Virus (13.2) Enveloped Virus (13.3) Complex Virus (13.5)
Background image of page 2
10/26/09 3 Culturing Viruses Phage Grown on a “lawn” of bacteria Each virus clears a spot called a “plaque” Animal viruses In living animals Or in chicken eggs (flu vaccine) Or in cell culture = Petri dish with animal cells Lytic Cycle of Bacteriophage T2 Attachment Tail fibers bind to bacterial cell wall Penetration Lysozyme digests cell wall Tail sheath contracts, tail core goes through Viral DNA enters cell Lytic Cycle cont. Biosynthesis
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/18/2011 for the course MICR 130 taught by Professor Umemoto during the Fall '09 term at University of Hawaii, Manoa.

Page1 / 9

Chapter13 - 10/26/09 Virus Size Chapter 13 Most are very...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online