104Lecture3

104Lecture3 - Lecture 3 EMBRANES Background reading 5 th...

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Unformatted text preview: Lecture 3 4/5/11 EMBRANES Background reading: 5 th edition text: Chapter 10, Pages 629-635, 642-648 4 th edition text: Chapter 10, Pages 593-601, 608-612 Outline: Membranes (continued) • Membrane proteins • Synthetic bilayers • Reconstitution of membranes • Asymmetry of membranes • Membrane fluidity • Membrane fusion • Transport of small molecules across membranes • Membrane Proteins α helix Integral membrane proteins: Proteins that span the membrane: Extend across membrane as α-helix of 20 – 30 amino acid residues Extend across membrane as a rolled-up β-sheet. Each strand in the barrel must be at least about 10 amino acids Some intrinsic membrane proteins are exposed at only one side of the membrane. NH 2 Other intrinsic membrane proteins are attached to the membrane with a lipid anchor or by an oligosaccharide chain linked to a lipid. Integral membrane proteins can be released from the membrane by dissociating the membrane with detergents. Peripheral membrane proteins:...
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This note was uploaded on 04/17/2011 for the course BIS 104 taught by Professor Scholey during the Winter '08 term at UC Davis.

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104Lecture3 - Lecture 3 EMBRANES Background reading 5 th...

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