Ch 43 Immunity - CHAPTER 43 THE BODYS DEFENSES The Nature...

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CHAPTER 43 THE BODY’S DEFENSES
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The Nature of Disease Pathogenic Organisms Pathogenic Organisms Genetic Disorders Genetic Disorders Toxic Chemicals Toxic Chemicals Other Environmental Factors Other Environmental Factors Physical Damage to Organs Physical Damage to Organs Nutritional Disorders Nutritional Disorders
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Types of Pathogenic Organisms Viruses Viruses Bacteria Bacteria Protozoan Protozoan Fungi Fungi Animal Animal Parasites Parasites
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Mechanisms of Disease by Pathogens Utilization of host nutritional Utilization of host nutritional resources resources Physical damage to host tissues Physical damage to host tissues Production of toxic substances Production of toxic substances Chromosomal and gene damage Chromosomal and gene damage Body cells behave abnormally Body cells behave abnormally
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Viruse s nucleic acid capsid envelope
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Bacteria cell wall plasma membrane cytoplasm circular DNA
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Defense Mechanisms 1. External defense 2. Internal Defense 3. Immune Defense
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Skin acts as barrier to microbes and viruses - sweat has a low pH Mucus traps foreign particles Tears - Lysozyme has antimicrobial action Gastric stomach acid 1 st Line of Defense
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Body Coverings:  The Skin sebaceous glands sweat gland epidermis
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Body Coverings:   Mucous Membranes mucus cilia columnar epithelium
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Phagocytic cells (WBCs) - N L M E B - Natural Killer (NK) Cells: attack virus infected cells Inflammatory Response Antimicrobial proteins - Lysozyme - Interferon - Antibodies 2 nd Line of Defense
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Nonspecific Phagocytosis Neutrophils Monocytes Eosinophils
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Mechanism of Phagocytosis Mechanism of Phagocytosis Mechanism of Phagocytosis Macrophage Macrophage
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Lymphatic System
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Inflammatory Response Histamine & prostaglandins released Capillaries dilate Clotting begins Chemotactic factors attract phagocytic cells Phagocytes consume pathogens & cell debris
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Characteristics of Immunity Recognition of self versus non-self Response is specific Retains a “memory” allowing an accelerated second response Can respond to many different materials Involves lymphocytes and antibodies
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Types of Immunity Active Immunity - Naturally-Acquired Active Immunity - Artificially-Acquired Active Immunity Passive Immunity - Naturally-Acquired Passive Immunity - Artificially-Acquired Passive Immunity
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Types of Acquired Immunity
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The production of antibodies against a specific disease by the immune system.
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This note was uploaded on 04/20/2011 for the course BIOL 172 taught by Professor Huddleston,m during the Spring '08 term at University of Hawaii, Manoa.

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Ch 43 Immunity - CHAPTER 43 THE BODYS DEFENSES The Nature...

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