faulty pathway

faulty pathway - likelihood that another family member will...

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ALOPECIA AREATA: Bald patches on the scalp ALOPECIA TOTALIS: Total loss of scalp hair ALOPECIA UNIVERSALIS: Hair lost on the entire body, including eyebrows, eyelashes and nose hair The cause of alopecia is still unknown, but the most accepted hypothesis states that it is a T-cell mediated autoimmune condition that is most likely to occur in genetically predisposed individuals. The affected hair follicles are attacked in groups by the person’s own immune system (the white blood cells), resulting in the halt of hair growth in that area. These follicles drastically slow down hair production. On a positive note, the stem cells that supply the follicle with new cells are not targeted, so the hair has the potential to regrow. Alopecia is also hereditary. In one out of every five persons with alopecia, someone else in the family has it too. Genetic factors determine the disease severity. If a person develops alopecia after the age of thirty for the first time, there is less
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Unformatted text preview: likelihood that another family member will have it. It has not been determined if environmental factors trigger the condition. Current research shows that something triggers the immune system to stop the hair follicle from growing, but it is still unknown. Scientists are not sure if it comes from the outside of the body like a virus or if it develops inside. Research suggests that people have genetic markers that increase their ability to develop alopecia. Alopecia is medically benign. People who have alopecia are often in excellent heath. The disease is only challenging emotionally for those who have extensive hair loss. There are several treatments for alopecia and the type of treatment depends on the person’s age and the amount of hair loss. Treatments do not turn off alopecia; they stimulate the hair follicle to produce hair again. They are used until the disease turns itself off. A result is most effective in milder cases....
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This note was uploaded on 04/19/2011 for the course BIOCHEM 2 taught by Professor Staff during the Spring '08 term at Emory.

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