Chapter 15 Cell Signaling

Chapter 15 Cell Signaling - Chapter 15: Cell Signaling and...

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Chapter 15: Cell Signaling and Communication I. Signal Transduction II. Signal a. nonpolar signals (i.e. steroids) would have intracellular receptors; these receptors will act as transcription factors. b. polar signals (i.e. peptides) would have transmembrane receptors (receptors outside the cell) c. In terms of the cells they signal, they can be divided into 3: i. Autocrine: signals secreted by a cell signals itself. ii. Paracrine: signals affect neighboring cells. iii. Endocrine: signals travel long distances (i.e. bloodstream) to its target. ***note: signals are specific to their receptors so it doesn’t matter how close or far the receptor is. III. Receptors a. Ion channels: The receptor changes conformation when stimulated by a signal. i. For example: ligand (signal) binds to its extracellular component. This allows for ions to go in/out.—i.e. acetylcholine channel. ii. It could also be light, sound, or change in electric charge. b.
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This note was uploaded on 04/19/2011 for the course LS 2 taught by Professor Pires during the Spring '08 term at UCLA.

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Chapter 15 Cell Signaling - Chapter 15: Cell Signaling and...

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