HN 612 Chapter 28

HN 612 Chapter 28 - Chapter 28: Liver, Biliary System &...

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1. Liver Physiology and Fuctions: a. Liver can regenerate i. Only 10-20% required to sustain life b. Integral to most metabolic functions i. Metabolism of macronutrients 1. 2. CHO: liver stores glycogen (glycogenesis) 3. CHO: gluconeogenesis from lactic acid, amino acids, TCA intermediates 4. Protein: transamination, deamination 5. 6. Fat: acetyl CoA made form fatty acids 7. Fat: synthesis of TGs, phospholipids, cholesterol, lipoproteins c. Integral to most metabolic functions i. Metabolism of macronutrients ii. Storage and activation of vitamins and minerals 1. Storage of fat soluble vitamins and B-12 2. Storage of Cu, Fe, Mg, Zn 3. Synthesis of transport proteins for Vit A, Cu, Fe, Zn 4. Activations: carotene to Vit A iii. Formation and excretion of bile iv. Conversion ammonia to urea 1. 75% of urea excreted by kidneys v. Metabolism of steroids 1. Detoxifies drugs and alcohol vi. Filter bacteria and flood chamber
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This note was uploaded on 04/19/2011 for the course HUMN NTR 612 taught by Professor Smith during the Spring '11 term at Ohio State.

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HN 612 Chapter 28 - Chapter 28: Liver, Biliary System &...

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