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ISB 202 10-23-08 - ISB 202 Lack of sensitivity to...

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ISB 202 10-23-08 Lack of sensitivity to antibiotics is a big problem Virus-non-cellular, non-living infectious particle o Has the following parts : A. nucleic acid (either DNA or RNA) Single or double strand of either (not both) B. usually coated with protein (may be “naked”) C. may be surrounded by an envelope o It cannot multiply by itself It must get a host cell to do it. Fortunately for us it requires a specific type of cell found only in certain species o Virus cannot be killed but can be deactivated o All of viruses parts are proteins o Where did viruses get that name??? o How do they multiply? 1. Virus attaches to host cell. Inserts DNA or RNA into cell 2. Virus uses host cell’s machinery to reproduce DNA/RNA and proteins 3. Virus assembles protein coat, DNA/RNA, and attaches protein tails (if part of the virus) o Virus makes enzymes that rupture the cell membrane, and the cell “lyses” (splits open) o The virus is released o If the virus has an envelope this is when the virus gets it from the host cell o The cells die o This is the lytic pathway of multiplication o There is another way viruses multiply This is the lysogenic pathway of multiplying
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