Candida albicans - Chad Davis Candida albicans Candida...

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Chad Davis Candida albicans Candida albicans is the most common fungus, causing 50-70% of all invasive candidiasis in the Candida species (1). Non- albicans species such as C. parapsilosis, C. glabrata, C. tropicalis and C. krusei make up approximately 17.1% of all nosocomial (blood stream) infections (1). Candidiasis is a fungal nosocomial infection that is a result of being treated in a hospital or any medical center (2). Finding the most efficient and proficient way(s) to differentiate these species of Candida is extremely crucial in patient survivability (1). Considering the 80% mortality rate of Candidiasis, differentiation in Candida species is important (1). Some of these non- albicans Candida species are resistant to polyene or azole antimycotics, and quickly diagnosing these species can eliminate any further progression of the infection (1). The risk factors of invasive Candidiasis are haematological or oncological malignancies which would be treated with chemotherapy or immunosuppressive treatment (1). Not including all other life supporting treatments, medicines and remedies that are implied along with the risk factors once diagnosed with Candidiasis (1). C. albicans, C. parapsilosis, C. glabrata, C. tropicalis and C. krusei are included in the Candida Genus which is in the Saccharomycetaceae Family, Order Saccharomycetales, Class Ascomycetes, Phylum Ascomycota and Kingdom Fungi (3). Invasive Candidiasis has unspecific symptoms and early detection is difficult, due to a lack of sensitivity in diagnostic tools to determine early detection (1). The first commercial test system is called Septifast® which is a "multiplex real-time PCR assay including Candida species" (1).
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Candida albicans - Chad Davis Candida albicans Candida...

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