Basic Principles of Renal Physiology

Basic Principles of Renal Physiology - renal tubules As the...

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Basic Principles of Renal Physiology Structure of the Kidney and Urinary System o Kidney external/internal anatomy Size: 10-12 cm x 5-7.5 cm x 2.5 cm Three general regions: Cortex: outer layer of the kidney Medulla (renal pyramid): consists of multiple (up to 18) renal pyramids Pelvis: minor (up to 13) / major (2-3) calyx to for pelvis Papilla, renal corpuscle, renal artery and renal vein, ureter o Summary of Kidney Function: Excrete most of the end-products of bodily metabolism Control the concentrations of most of the constituents (water and solutes) of the bodily fluids As blood passes through the kidneys, all of the blood cells/plasma proteins and about 80% of plasma volume remain within the renal blood vessels About 20% of the plasma volume is filtered out of the blood vessels and into the
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Unformatted text preview: renal tubules As the filtered plasma passes through the different parts of the tubules, its composition and volume are modified by reabsorption and secretion processes, involving active and passive transports of water and specific solutes The tubules ultimately join together to form the ureter and the fluid remaining in the tubules moves into the ureter as urine for excretion The altered plasma is transported by the circulatory system to all organs of the body, where water and solutes are exchanged between blood plasma and interstitial fluid By altering blood plasma, the kidneys regulate the osmolarity and solute composition of interstitial fluid throughout the body...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

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Basic Principles of Renal Physiology - renal tubules As the...

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