Cell membrane

Cell membrane - adhere only temporarily to the biological...

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Cell membrane: phospholipid bilayer which surrounds a cell and protects and encloses the cytoplasm, about 4nm thick, fluid mosaic model – proteins embedded in membrane o Phospholipid: Two fatty acids esterified to a glycerol, with a phosphate at the third carbon, basic molecule is phosphatidic acid, phosphate is also esterified to an alcohol, named "phosphatidyl ________", where the blank is the name of the alcohol - typically serine, ethanolamine, choline or inositol; forms a bilayer (hydrophobic heads meet hydrophilic tails), semi-fluid o Integral membrane proteins (include transmembrane proteins): permanently attached to cell membrane o Peripheral membrane proteins:
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Unformatted text preview: adhere only temporarily to the biological membrane with which they are associated o Lipid-anchored proteins: covalently attached fatty acid such as palmitate or myristate serves to anchor them to either face of the cell membrane o Unsaturation: regulates membrane fluidity, in conjunction with cholesterol, more unsaturation = more fluidity o Cholesterol: regulates membrane fluidity, in conjunction with unsaturation, cell membrane component, serves to keep membranes fluid at low temperatures, yet reduces fluidity at high temperatures o Arachidonic acid: unsaturated, forms leukotrienes when catalyzed by lipoxygenase...
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