Cell proliferation and repair

Cell proliferation and repair - Neovascularization...

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o Cell proliferation and repair: (days to 2 weeks) in response to growth factor release, especially FGF, neighborhood fibroblasts proliferate, migrate into the wound and deposit large amounts of extracellular matrix Myofibroblasts: cell that is in between a fibroblast and a smooth muscle cell in differentiation Wound contraction: muscles pull skin back together, as it should be.
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Unformatted text preview: Neovascularization (angiogenesis): necessary to sustain newly forming tissue, promoted by FGF and Vascular Endothelial Growth Factor (VEGF), which is released in hypoxic environments, stimulates new vessel formation Vascular Endothelial Growth Factor (VEGF): c hemical signal produced by cells that stimulates the growth of new blood vessels...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

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