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Unformatted text preview: surfaces), provides for directional and regulated transport o Apical: surface of the plasma membrane that faces the lumen Lumen: inside space of a tubular structure, such as an artery or intestine.  By extension, a lumen can also be the inside space of a cellular component or structure (inner membrane) o Basolateral: surface of the plasma membrane that forms its basal and lateral surfaces. It faces towards the interstitium, and away from the lumen Interstitium: solution that bathes and surrounds the cells of multicellular animals (outer membrane) Cystic Fibrosis Transconductance Regulator (CFTR): member of the ABC superfamily of transport proteins, does not appear to act as an active transporter - chloride channel facilitated diffusion, activated by phosphorylation , permits chloride movement to the epithelial surface - results in osmotic flux of water to the apical surface, diluting mucus, when broken, CF...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.
- Spring '11