This preview shows page 1. Sign up to view the full content.
Unformatted text preview: catalytic subunits, described by a modified Michaelis-Menten equation • SNARE: membrane proteins which bind to one another and help pull vesicle and cell membranes together, “Vesicular” vSNARE extends from the vesicle membrane, while“Target” tSNARE extends from the cell membrane (in this case) o Synaptobrevin: vSNARE found in synaptic vesicles containing neurotransmitters, cut by tetanus and botulisum toxins • Intestinal epithelium: epithelium that covers the small and large intestine. It is simple columnar and nonciliated, where the botulism toxin crosses into the bloodstream • Light chain: small polypeptide subunit of a protein complex • Zinc endopeptidase: cleaves synaptobrevin (no synaptobrevin, no vesicle fusion, no neurotransmitter release à paralysis)...
View Full Document
This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.
- Spring '11