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Quick Facts- ALS

Quick Facts- ALS - o 5,000 in the US annually o Prevalence...

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ALS: Invariably fatal Symptoms o Muscle weakness in hands, arms, legs, or in the muscles of speech, swallowing or breathing o Fasciculation and cramping of muscles o Eventual paralysis of arms, legs, and most voluntary muscles o Difficulty in projecting the voice o Difficulty swallowing o Difficulty in breathing Sensation remains intact Incidence and prevalence
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Unformatted text preview: o 5,000+ in the US annually o Prevalence in the US is around 20,000 • Sporadic ALS (SALS) o 90-95% of cases o Etiology is unknown • Familial ALS (FALS) o 5-10% of cases o Mutations in certain genes, most of which are unknown o A mutation in the superoxide disumutase gene (SOD1) is one of the few known...
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