Quick Facts- Asthma and Cystic Fibrosis

Quick Facts- Asthma and Cystic Fibrosis - most common...

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Wounds: Triggered in response to cell death, destruction of extracellular connective tissue, loss of blood vessel integrity Asthma: Definition: Reversible airways obstruction not due to any other disease. Symptoms: o Coughing, wheezing and shortness of breath. o Chest pain o Expectoration of thick, stringy mucus In severe attacks: o Rapid breathing o Cyanosis, indicating hypoxia o Respiratory acidosis from hypoventilation o Death – from respiratory failure Cystic fibrosis: An inherited disease that causes the body to produce an abnormally thick, sticky mucus on epithelial surfaces. Prevalence: Affects approximately 30,000 children and adults in the United States. It is one of the
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Unformatted text preview: most common lethal inherited disorders among Caucasians (1 in 3,200) One in 31 Americans (one in 28 Caucasians) is an unknowing, symptom-less heterozygous carrier of the defective gene Prognosis: In 2005, the median survival age was 36.8 years, and slowly increasing. Decreased mucociliary clearance of sputum leads to chronic endobronchial bacterial colonization, and o Production of large amounts of sputum o Wheezing o Dyspnea o Limited exercise tolerance o Death Pancreatic insufficiency in 85% of patients, leading to malabsorption of fat and malnutrition. Also diabetes mellitus, bowel obstructions, arthritis, and infertility....
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

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