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Unformatted text preview: form the myelin sheaths of the central nervous system Nodes of Ranvier: area between myelin sheaths; causes salutatory connections Myelin basic protein: in the ogliodendocyte membrane; o presented by the oglidendrocyte as a prospective antigen in people with MS, then recognized as foreign by T cells; after this, lymphocytes induce apoptosis of ogliodendrocytes and macrophages, destroy the ogliodendrocytes; slows conduction greatly, weakness and lack of coordination results o leukocytes accumulate in the area of degenerated Schwann cells; inflammation squishes the neuron, sometimes killing it; anesthesia, paralysis, and granulomas result Treatments: immunosuppressants, interferons, decoy molecules, T cell vaccination (induce an immune response against TCRs); long-term cocktail of antimicrobials...
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- Spring '11