Representative Neurotransmitters

Representative Neurotransmitters - in emotion and...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Representative Neurotransmitters Acetylcholine (Ach): concentrated in motorneurons ( at the skeletal neuromuscular junctions), pyramidal cells of motor cortex, neurons in basal ganglia and parasympathetic division of the autonomic nervous system (at the neuro-effector junctions); has two types of receptors (nicotinic AChR and muscarinic AChR); excitatory Dysfunction: myasthenia gravis (MG), Lambert-Eaton syndrome (LES or ELS) Norepinepherine (NE): concentrated in neurons in brain stem, hypothalamus, and sympathetic division of the autonomic nervous system; involved in arousal, dreaming, and regulation of mood; excitatory in most cases, some inhibitory Dopamine (DA): concentrated in neurons in substantia nigra – a striatal region of basal ganglia; involved
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: in emotion and subconscious movements of skeletal muscles; inhibitory Dysfunction: Parkinson’s Seratonin (5-HT): concentrated in neurons in brain stem; involved in inducing sleep, temperature regulation, sensory perception and regulation of mood; excitatory Dysfunction: lack of serotonin leads to depression Glycine: released by spinal cord inhibitory neurons, involved in motor control; inhibitory Gamma aminobutyric acid (GABA): released by neurons in spinal cord, cerebellum, basal ganglia, and cerebral cortex; involved in variety of function; inhibitory Dysfunction: likely target for Valium (anti-anxiety drug) Glutamate: released by neurons in sensory pathways and cerebral cortex, involved in a variety of functions; excitatory...
View Full Document

This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

Ask a homework question - tutors are online