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Unformatted text preview: o Immune complexes: multivalent antibodies (can bind multiple antigens), can cross-link antigens; facilitates phagocytosis, degranulation of granulocytes, activation of the complement system Immunoprecipitation: antibodies cross-linked with antigen can form a precipitate o Antibody classes: IgX, where Ig stands for immunoglobin IgG: the bulk of secreted antibody, against blood-borne antigens; as much as 20% of serum protein IgD: another antigen receptor on B cells IgM: antigen receptor on B cell surface, and the first class generated in an immune response, much larger than IgG IgA: against mucosal (epithelial) antigens IgE: bind to mast cells, and trigger degranulation and the classic allergic reaction...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.
- Spring '11