Immune Response

Immune Response - cells, part of what is called innate...

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Both Leprosy and multiple sclerosis involve direct, unwanted effects of immune system on impeding nerve conduction Autoimmune disease: self becomes recognized as foreign Antigen: substance capable of inducing an immune response Auto-antigen: a self protein that is recognized as an antigen in autoimmune disease Epitope: a discrete part of an antigen that is antigenic; can be many epitopes / antigen Antibody: a protein that binds tightly to specific epitopes for identification and elimination. Anaphylaxis: a systemic allergic reaction (as opposed to a localized allergic reaction) Proliferate: cells divide and become more numerous Differentiate: a cell becomes more specific in its structure and function Immune response: responds to a wide array of antigens, can respond to the one antigen that is present rather than all antigens, previously encountered antigens evoke a faster response on subsequent encounters o Complement system: an enzyme system in the blood that can directly kill some foreign
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Unformatted text preview: cells, part of what is called innate immunity o Humoral immune response: antibodies bind to and inactivate antigens o Cell-mediated immunity: cells respond directly and actively to eliminate antigens Granulocytes: Often called polymorphonucleocytes (PMNs) because of their multilobed nuclei o Neutrophils: membrane ruffles, granular, phagocytosis, chemical attack on bacteria and other foreign objects through degranulation Phagocytosis: process of a cell engulfing solid particles. The vesicle in which the object now resides is a phagosome o Basophils: leave the tissue to become mast cells, release substances that increase vascular permeability and recruit other immune cells - inflammation o Eosinophils: generally involved in attacks on parasites and multicellular organisms Monocytes/Macrophages: large nucleus, membrane ruffles, lysosomes, phagocytosis, antigen display (a.k.a. antigen presentation)...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

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