• Yield from 1 glucose : 2 ATP from the glycolytic pathway + 2 ATP from the TCA cycle +30 ATP from oxidative phosphorylation via NADH + 4 ATP from oxidative phosphorylation via FADH2 = 38 ATP/glucose (maximum theoretical yield) Complete reaction o C6H12O6 + 6O2 + 38ADP + 38 Pi 6CO2 + 38 ATP + 44 H2O • Anaerobic: in the absence of O2, substrates are converted to either ethanol and CO2 (yeast) or lactate (you) o Glycolysis: breakdown of glucose to yield energy, refers specifically to the anaerobic portion of the metabolic pathway, products may be broken down further by oxidative or non-oxidative reactions, breakdown of glucose, a 6-carbon sugar, into two pyruvate molecules; basic steps: preparation and cleavage, oxidation, pyruvate formation; takes place in cytoplasm (glucose +2NAD + + 2ADP + 2Pi à 2 pyruvate + 2NADH + 2H + + 2H 2 O + 2ATP) virtually all known cells depend upon this pathway; the fate of these molecules and the amount of ATP generated depends on the availability of oxygen; fast! Preparation and cleavage:
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.