Multiple sclerosis

Multiple sclerosis - autoimmune attack against...

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Multiple sclerosis: slowly progressive CNS disease characterized by patches of demelination in the brain and spinal cord, resulting in multiple and varied neurologic symptoms; weakness and clumsiness, stiffness and gait disturbances, visual disturbances, mental disturbances, including lack of judgement, unprovoked weeping/laughter; more common further from equator, in women, in people aged 20-40, rate of 75/10000 in the US; $6.8 billion annually; unknown etiology,
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Unformatted text preview: autoimmune attack against ogliodendrocytes, which are cells that form the myelin sheath in the CNS nerves, classified by progression of symptoms o Benign: attack, improvement, no deficit o Relapsing-remitting: attack, improvement, deficit (majority) o Secondary progressive: attack, improvement, deficit, attack o Primary progressive: initial attack, no remission...
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This note was uploaded on 04/23/2011 for the course BIME 2102 taught by Professor Kim during the Spring '11 term at UVA.

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