310-27 - CH 310 N LECTURE 27 Textbook Assignment: Chap 21...

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1 CH 310 N LECTURE 27 Homework (for credit): POW 9 posted (Due Apr 4) Today’s Topics: Medicinal Chemistry Topic: Synthetic Opiates XM 2 Grades Posted to BB 2 Receptor Sites and Drug Design Case Study: Opiates
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3 The lock and key model. A substrate is a substance whose reactions are catalyzed by an enzyme. Here- a drug occupying the receptor site of the natural substrate. 10.5 Drug interactions at the cellular level Medicinal Chemistry 4 The functional groups and their placement in three-dimensional space determines to a large degree a molecule’s biological activity. The portion of a molecule that determines the biological effects of a drug is called the pharmacophore. Medicinal Chemistry
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5 Medicinal Uses for Morphine: ± as an adjunct to general anesthesia ± in epidural anesthesia or intrathecal analgesia ± for palliative care (i.e. to alleviate pain without curing the underlying reason for it, usually because
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This note was uploaded on 04/24/2011 for the course CH 56255 taught by Professor Colapret during the Spring '11 term at University of Texas at Austin.

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310-27 - CH 310 N LECTURE 27 Textbook Assignment: Chap 21...

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