lecture5 - steroids. 2.Masculinizing and Feminizing...

Info iconThis preview shows pages 1–15. Sign up to view the full content.

View Full Document Right Arrow Icon
Hormones Chemical substances - produced by endocrine glands - secreted into the blood - circulate throughout the entire body. - target tissues respond to hormones.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Target tissues
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Hormones you are responsible for: Sex Hormones – Produced by the gonads : Androgens: Testosterone, Androstenedione, DHT, Androstenediol Estrogens: Estradiol, Estrone Progesterone Gonadotropins – Produced by the pituitary: Luteninizing Hormone (LH) Follicle Stimulating Hormone (FSH) Gonadotropin Releasing Hormone (GnRH) – Produced by the hypothalamus
Background image of page 4
Steroid Biosynthetic Pathway Pregnenolone Progesterone 17-OH Pro .. Androsteno- dione Testosterone Androsteno- dio l Dehydro… 17-Preg …. Cortiso…l Corticosterone Estradio l Estrone 11-Deoxy .. Deoxy…. Aldosterone 17-OH Cort Cholesterol 21-OH 11-OH Aromatase Aromatase 21-OH 11-OH 3B-HSO 3B-HSO 3B-HSO 3B-HSO CYP-17 CYP-17 CYP-17 Lyase Lyase 17B-HSO 17B-HSO
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
What you need to know about the Steroid Biosynthetic Pathway 1.Cholesterol is the precursor to the all of the
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 12
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 14
Background image of page 15
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: steroids. 2.Masculinizing and Feminizing hormones utilize the same biosynthetic pathway. No step in the pathway can be skipped. 3.Masculinizing and Feminizing hormones are very similar in size and chemical composition. 4.The main difference is that estrogens have aromatic rings. Testosterone Testosterone at Puberty Estrogen at Puberty Negative Feedback System Testes (Interstitial Cells Produce Testosterone) LH Testosterone Hypothalamus - Thermostat Pituitary Gland Produces LH Negative Feedback System Testes (Sertoli cells regulate sperm production) FSH Sperm Hypothalamus - Thermostat Pituitary Gland Produces FSH Ejaculation Negative Feedback System Testes (Sertoli cells produce Inhibin) Stops FSH Inhibin No sperm produced Hypothalamus - Thermostat Pituitary Gland Produces FSH...
View Full Document

This note was uploaded on 04/24/2011 for the course BIO 388n taught by Professor Shank during the Spring '11 term at California State University Los Angeles .

Page1 / 15

lecture5 - steroids. 2.Masculinizing and Feminizing...

This preview shows document pages 1 - 15. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online